Zepbound® prescription online for weight loss
Together with LillyDirect®, Simple Scripts now offers authentic Zepbound (tirzepatide) in a vial. Shipped directly to you, it’s the most convenient way to start your weight loss journey.
- A new way to access FDA-approved GLP-1s
- The fastest way to lose weight, now at the lowest price ever*
- Targets two hormone receptors to curb hunger
What is Zepbound?
How is Zepbound different from Ozempic® or Wegovy®?
Zepbound and Wegovy are approved by the FDA for weight loss, while Ozempic is approved for the treatment of type 2 diabetes, but can be prescribed off-label for weight loss, if appropriate.
The main difference between these medications is the active ingredient. Ozempic and Wegovy use semaglutide, while Zepbound uses tirzepatide. Tirzepatide is a dual-action GLP-1 and GIP, meaning it works by activating two receptors to curb hunger and regulate your metabolism, helping you feel full faster and longer. In comparison, semaglutide only activates the GLP-1 receptor.
What’s the difference between Zepbound pens and vials?
What’s the difference between Zepbound pens and vials?
Zepbound pens and vials are the exact same FDA-approved medications and are available in the same doses. This means that whether you take Zepbound via a syringe or pen, both dosage forms have the same efficacy and side effects. On average, people on Zepbound lose 20% of their weight in a year.*
Key differences:
Zepbound vials are administered with a syringe and vial, while Zepound pens are prefilled autoinjector pens.
Zepbound vials can be shipped conveniently and directly to you from the LillyDirect partner pharmacy, while Zepbound pens can only be fulfilled through your preferred pharmacy.
Zepbound vials are only available as a cash pay offering, and are not eligible for insurance coverage. Zepbound pens are available as a cash pay offering or through insurance coverage.
Visualize Your Transformation
Use the calculator below to see what a 20% weight reduction could look like for you. Simply adjust the slider to your current weight to discover your goal.
current weight
could lose (lbs):
What's included in the Simple Scripts Body membership?
- Access to FDA-approved GLP-1 medications
- Dedicated insurance concierge
- Unlimited provider messaging
- Side effect management and titration support
- Weight tracking and dose logging
- 1:1 health coaching
Explore your GLP-1 options
- A full suite of GLP-1 options to fit your needs
- Options include Wegovy pill, Wegovy pen, Ozempic, Zepbound pen, and Zepbound vial
- Insurance or cash-pay
Zepbound FAQs
Can I get Zepbound through Ro?
What’s the difference between Zepbound pens and vials?
What’s the difference between Zepbound pens and vials?
Zepbound pens and vials are the exact same FDA-approved medications and are available in the same doses. This means that whether you take Zepbound via a syringe or pen, both dosage forms have the same efficacy and side effects. On average, people on Zepbound lose 20% of their weight in a year.*
Key differences:
Zepbound vials are administered with a syringe and vial, while Zepound pens are prefilled autoinjector pens.
Zepbound vials can be shipped conveniently and directly to you from the LillyDirect partner pharmacy, while Zepbound pens can only be fulfilled through your preferred pharmacy.
Zepbound vials are only available as a cash pay offering, and are not eligible for insurance coverage. Zepbound pens are available as a cash pay offering or through insurance coverage.
What are the side effects of Zepbound?
Like other GLP-1 medications, Zepbound comes with the risk of potential side effects. Most people experience these side effects when their dose is increased, and they tend to improve once a steady dose is reached. Some of the most common side effects include:
- Nausea
- Diarrhea
- Vomiting
- Constipation
- Stomach pains
- Upset stomach
- Indigestion
- Injection-site reactions
- Fatigue
- Belching and gas
- Hair loss
- Heartburn
Additionally, if you take oral birth control pills, talk to your healthcare provider before you use Zepbound. Birth control pills may not work as well while using Zepbound. Your healthcare provider may recommend another type of birth control for 4 weeks after you start Zepbound and for 4 weeks after each increase in your dose of Zepbound.
More severe side effects are rarer but possible. Serious side effects include:
- Thyroid cancer: Zepbound may cause tumors in the thyroid, including thyroid cancer. Watch for possible symptoms, such as a lump or swelling in the neck, hoarseness, trouble swallowing, or shortness of breath. If you have any of these symptoms, tell your healthcare provider. Do not use Zepbound if you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC) or if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
- Severe stomach problems
- Pancreatitis
- Gallbladder disease
- Rapid heartbeat
- Severe allergy (hypersensitivity)
- Low blood sugar
- Changes in vision in patients with type 2 diabetes
- Kidney disease
- Suicidal thoughts or behaviors
- Pulmonary aspiration during general anesthesia or deep sedation: . In rare instances, some patients undergoing anesthesia during surgical procedures have had stomach contents enter their lungs, which can cause pneumonia and other problems.
You can report quality complaints and side effects to The Lilly Answers Center (TLAC) at +1(800) 545-5979 to notify Lilly, the manufacturer of your medication. They use side effect information to monitor and sometimes report on drug safety.
These are not all of the possible side effects of Zepbound. For more complete information about Zepbound, including Boxed warning, see full Important Safety Information.
How do you store Zepbound?
Both Zepbound pens and vials should be stored in the refrigerator at 36-46º F, but they may be kept between 46-86º F for up to 21 days, if needed. Store unopened pens and vials in their original cartons to protect them from light.
If you store Zepbound pens at room temperature, do not return them to the refrigerator. Do not freeze the pens. The pen contains glass parts, so if you drop the pen on a hard surface, do not use the pen for your injection.
If you store Zepbound vials at room temperature, throw away any unused portion after 21 days. Do not freeze the medication, and do not use it if it has been frozen. Be sure to throw away any opened vial after using it, even if there is medication left in the vial.
How much does Zepbound cost?
This depends whether you’re prescribed Zepbound single-dose pens or vials.
For Zepbound pens, insurance coverage and copays will vary depending on your plan. Our insurance concierge will work with your provider to determine your coverage for GLP-1 medication and, if necessary, submit a prior authorization request for you. If you’re paying cash, Zepbound pens cost about $1,050/mo. If you have commercial insurance, you may be eligible for a discount through the manufacturer. Learn more about the Zepbound savings card here.
Zepbound vials are available as a cash pay-only offering through LillyDirect®:
- $299/mo for 2.5 mg dose
- $399/mo for 5 mg dose
- $449/mo for 7.5 mg, 10 mg, 12.5 mg, and 15 mg doses (with manufacturer offer)
More on the manufacturer offer: LillyDirect is offering the 7.5 mg, 10 mg, 12.5 mg, and 15 mg doses of Zepbound vials at a discounted $449/mo price.
To keep this discounted price for 7.5 mg, 10 mg, 12.5 mg, and 15 mg refills: You must complete your next refill check-in within 45 days of your last delivery.
What happens if you miss the 45-day window? You’ll be charged the full price for your refill:
- $499 for a 7.5 mg refill
- $699 for 10 mg, 12.5 mg, and 15 mg refills
We’ll send you reminders to complete your refill check-in as the 45-day deadline gets closer.
Medication costs are separate from your Ro Body membership ($45 first month, $145/mo thereafter), which includes our insurance concierge, provider visits, ongoing coaching, and anytime messaging. Learn more about pricing here.