FDA-approved GLP-1s at the lowest prices. See if you qualify

Transparent pricing, always

The total price of your treatment plan may vary based on number of doses and shipping frequency. Complete an online visit to see if prescription treatment is right for you.

Erectile dysfunction

Pricing for Viagra (brand name and generic), sildenafil (the active ingredient in Viagra), and Cialis (brand name and generic).

Healthcare professionals on the Simple Scripts platform will work with you to understand your symptoms and goals and recommend a treatment plan they think will be most effective. You can let the doctor or nurse practitioner know any preferences you have based on price and it will be taken into consideration as well.

Your total cost may vary based on number of doses and shipping frequency. Complete an online visit to see if prescription treatment for ED is right for you.

Simple Scripts SparksRX Sildenafil 55mg, Tadalafil 22mg

4x dose plan$48/mo

6x dose plan$72/mo

8x dose plan$96/mo

10x dose plan$120/mo

Daily Rise GummiesRX Tadalafil 7mg

1-month (30 doses)$89/mo

3-month (90 doses)$69/mo

Generic ViagraRX Sildenafil

25 mg$4

50 mg Most popular$6

100 mg$10

Branded ViagraRX Sildenafil

25 mg$90

50 mg Most popular$90

100 mg$90

Generic of CialisRX Tadalafil

5 mg$11

10 mg Most popular$44

20 mg$44

Daily Generic of Cialis RX Tadalafil

2.5 mg Most popular$8

5 mg $8

Branded CialisRX Tadalafil

5 mg Most popular$20

10 mg $80

20 mg $8<0/span>

Side effects

These are the recorded side effects for PDE5 inhibitors, the class of drug which each of our treatments fall under.

Before taking any PDE5 inhibitor, you should know: People who are taking organic nitrates (e.g., Im-Dur, Nitrobid, Isordil) or nitrites should not take PDE5 inhibitors, as the combination can reduce blood pressure to dangerously low levels. People with cardiovascular conditions who have been advised by a healthcare professional to avoid sexual activity should not take PDE5 inhibitors, as they can worsen cardiovascular conditions. You or a caregiver should carefully monitor for these side effects, especially in the beginning of treatment.

Discuss it all with your healthcare provider

Concerned about the potential side effects of treatment? Not a problem. You’ll be matched with a US-licensed healthcare professional who will offer guidance, answer your questions, and help if you experience any side effects.

Simple Scripts

Cardiac risk of sexual activity: ED medication should not be used by men for whom sexual activity is not advised because of their underlying cardiovascular status.

Combination with other PDE-5 inhibitors: This compounded medication contains two prescription PDE-5 inhibitors, sildenafil and tadalafil. Monitor for signs of severely low blood pressure, such as dizziness or fainting, or prolonged erection. Do not take this medication more than once in a 24-hour period or within 24 hours of any other ED medications or products that contain tadalafil or sildenafil.

Prolonged erections: Seek immediate emergency treatment for an erection lasting more than 4 hours.

Effects on the eye: Seek medical care and stop medication if you experience a sudden loss of vision in one or both eyes. Sudden loss of vision could be a sign of non arteritic anterior ischemic optic neuropathy (NAION).

Sudden hearing loss: Stop medication and seek prompt medical attention if you experience a sudden decrease or loss of hearing, which may be accompanied by ringing in the ears.

Co-administering with alpha-blockers or other blood pressure-lowering drugs: If you are taking a medication to lower your blood pressure or taking an alpha-blocker, sildenafil may increase the blood-pressure lowering effect, leading to a sudden drop in blood pressure. When starting sildenafil, monitor carefully for signs of too low blood pressure, including dizziness, lightheadedness, or fainting.

Co-administering with ritonavir: If you are taking a medication called ritonavir at the same time as taking sildenafil, ritonavir can increase the amount of sildenafil in your system. Monitor for lowered blood pressure, fainting, and prolonged erection.

Effects on bleeding: Sildenafil has no effect on bleeding time when taken alone or with aspirin; however, there have been reports of bleeding with use of sildenafil. Tell your Ro-affiliated provider if you have a bleeding disorder or ulcers.

Alcohol: Drinking large amounts of alcohol (>5 units) with sildenafil can increase the potential of a sudden drop in blood pressure.

Sexually transmitted infections: Sildenafil does not protect against sexually transmitted diseases. Use safe sex practices.

What are the most common side effects of sildenafil? Headache

Flushing
Indigestion
Abnormal vision
Nasal congestion
Back pain
Muscle pain
Nausea
Dizziness
Rash

You are encouraged to report negative side effects of prescription products to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Important safety information

These are the recorded side effects for PDE5 inhibitors, the class of drug which each of our treatments fall under.

Before taking any PDE5 inhibitor, you should know: People who are taking organic nitrates (e.g., Im-Dur, Nitrobid, Isordil) or nitrites should not take PDE5 inhibitors, as the combination can reduce blood pressure to dangerously low levels. People with cardiovascular conditions who have been advised by a healthcare professional to avoid sexual activity should not take PDE5 inhibitors, as they can worsen cardiovascular conditions.

Discuss it all with your healthcare provider

Concerned about the potential side effects of treatment? Not a problem. You’ll be matched with a US-licensed healthcare professional who will offer guidance, answer your questions, and help if you experience any side effects.

Simple Scripts

What is the FDA-approved use of sildenafil?

Sildenafil is a phosphodiesterase-5 (PDE5) inhibitor indicated for the treatment of erectile dysfunction (ED).Your Ro-affiliated provider may prescribe Sparks, which contains both sildenafil 55 mg and tadalafil 22 mg, as a compounded drug to treat erectile dysfunction. Compounded drugs are permitted to be prescribed under federal law, but are not FDA-approved and do not undergo safety, effectiveness, or manufacturing review.

Who should not use sildenafil?

Do not use sildenafil if: You are taking a class of medications called nitric oxide donors, including organic nitrates or organic nitrites in any form. Sildenafil can increase the blood pressure-lowering effect of nitrates. You have a known allergic reaction to sildenafil. You are taking a class of medications called guanylate cyclase (GC) stimulators, such as riociguat. Sildenafil can increase the blood pressure-lowering effect of these medications.

How should I take Sparks?

Place the lozenge under your tongue and let it dissolve. Take at least 15 minutes before having sex. You can take the medication with or without food. However, do not eat or drink anything while the product is under your tongue. Avoid excessive consumption of alcohol. You should take the medication exactly as prescribed. Do not take this medication more than once in a 24-hour period or within 24 hours of any other ED medications or products that contain tadalafil or sildenafil. If your symptoms are not improving or you have any questions about changing or stopping medication, reach out to your Ro-affiliated provider for guidance.

What should I tell my Ro-affiliated provider before using sildenafil?

Sildenafil has many drug interactions. It’s important to tell your Ro-affiliated provider all of the medications you are currently taking, including prescription, over-the-counter medications, vitamins, and herbal and dietary supplements. Some medications to watch out for include: Nitrates, alpha-blockers, and antihypertensives: When these medications are taken with sildenafil, a sudden drop in blood pressure can occur. CYP3A4 inhibitors, such as ritonavir, ketoconazole, and itraconazole and erythromycin: These medications increase sildenafil exposure, which can cause a sudden drop in blood pressure and prolonged erection. Alcohol: Drinking large amounts of alcohol (>5 units) with this product can increase the potential of a sudden drop in blood pressure.It’s important to share your entire medical history with your provider. In particular, tell your provider if you have or have a past history of: Cardiovascular risk that prevents you from partaking in sexual activity Chest pain requiring nitroglycerin Predisposition to priapism (painful erection that lasts >4 hours) Benign prostatic hyperplasia (BPH) and are being treated with alpha-blockers Ventricular outflow obstruction (e.g. aortic stenosis, idiopathic hypertrophic subaortic stenosis) Severely impaired autonomic control of blood pressure Myocardial infarction, stroke, or life-threatening arrhythmia Low or high blood pressure Cardiac failure or coronary artery disease causing unstable angina Anterior ischemic optic neuropathy (NAION) or a “crowded” optic disc. Bleeding disorders or ulcers Kidney or liver disease Pulmonary hypertension Retinitis pigmentosaWithholding or providing inaccurate information about your health and medical history in order to obtain treatment may result in harm, including, in some cases, death.What are the most serious side effects that I or a caregiver should monitor for when taking sildenafil? If you are experiencing a medical emergency, call 911 or seek immediate medical attention. You or a caregiver should carefully monitor for these side effects, especially in the beginning of treatment. Cardiac risk of sexual activity: ED medication should not be used by men for whom sexual activity is not advised because of their underlying cardiovascular status. Combination with other PDE-5 inhibitors: This compounded medication contains two prescription PDE-5 inhibitors, sildenafil and tadalafil. Monitor for signs of severely low blood pressure, such as dizziness or fainting, or prolonged erection. Do not take this medication more than once in a 24-hour period or within 24 hours of any other ED medications or products that contain tadalafil or sildenafil. Prolonged erections: Seek immediate emergency treatment for an erection lasting more than 4 hours. Effects on the eye: Seek medical care and stop medication if you experience a sudden loss of vision in one or both eyes. Sudden loss of vision could be a sign of non arteritic anterior ischemic optic neuropathy (NAION). Sudden hearing loss: Stop medication and seek prompt medical attention if you experience a sudden decrease or loss of hearing, which may be accompanied by ringing in the ears. Co-administering with alpha-blockers or other blood pressure-lowering drugs: If you are taking a medication to lower your blood pressure or taking an alpha-blocker, sildenafil may increase the blood-pressure lowering effect, leading to a sudden drop in blood pressure. When starting sildenafil, monitor carefully for signs of too low blood pressure, including dizziness, lightheadedness, or fainting. Co-administering with ritonavir: If you are taking a medication called ritonavir at the same time as taking sildenafil, ritonavir can increase the amount of sildenafil in your system. Monitor for lowered blood pressure, fainting, and prolonged erection. Effects on bleeding: Sildenafil has no effect on bleeding time when taken alone or with aspirin; however, there have been reports of bleeding with use of sildenafil. Tell your Ro-affiliated provider if you have a bleeding disorder or ulcers. Alcohol: Drinking large amounts of alcohol (>5 units) with sildenafil can increase the potential of a sudden drop in blood pressure. Sexually transmitted infections: Sildenafil does not protect against sexually transmitted diseases. Use safe sex practices.

What are the most common side effects of sildenafil?

Headache Flushing Indigestion Abnormal vision Nasal congestion Back pain Muscle pain Nausea Dizziness RashYou are encouraged to report negative side effects of prescription products to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.This information is not comprehensive. Please see the full Prescribing Information for complete safety information.

What is the FDA-approved use of tadalafil?

Tadalafil is a phosphodiesterase-5 (PDE5) inhibitor indicated for the treatment of erectile dysfunction (ED). Your Ro-affiliated provider may prescribe Sparks, which contains both sildenafil 55 mg and tadalafil 22 mg, as a compounded drug to treat erectile dysfunction. Compounded drugs are permitted to be prescribed under federal law, but are not FDA-approved and do not undergo safety, effectiveness, or manufacturing review.

Who should not use tadalafil?

Do not use tadalafil if: You are taking a class of medications called nitric oxide donors, including organic nitrates or organic nitrites in any form. Tadalafil can increase the blood pressure-lowering effect of nitrates. You have a known allergic reaction to tadalafil. You are taking a class of medications called guanylate cyclase (GC) stimulators, such as riociguat. Tadalafil can increase the blood pressure-lowering effect of these medications.

How should I take Sparks?

Place the lozenge under your tongue and let it dissolve. Take at least 15 minutes before having sex. You can take the medication with or without food. However, do not eat or drink anything while the product is under your tongue. Avoid excessive consumption of alcohol. You should take the medication exactly as prescribed. Do not take this medication more than once in a 24-hour period or within 24 hours of any other ED medications or products that contain tadalafil or sildenafil. If your symptoms are not improving or you have any questions about changing or stopping medication, reach out to your Ro-affiliated provider for guidance.What should I tell my Ro-affiliated provider before using tadalafil? Tadalafil has many drug interactions. It’s important to tell your Ro-affiliated provider all of the medications you are currently taking, including prescription, over-the-counter medications, vitamins, and herbal and dietary supplements. Some medications to watch out for include: Nitrates, alpha-blockers, and antihypertensives: When these medications are taken with tadalafil, a sudden drop in blood pressure can occur. CYP3A4 inhibitors, such as ritonavir, ketoconazole, and itraconazole and erythromycin: These medications increase tadalafil exposure, which can cause a sudden drop in blood pressure and prolonged erection. Alcohol: Drinking large amounts of alcohol (>5 units) with tadalafil can increase the potential of a sudden drop in blood pressure.It’s important to share your entire medical history with your provider. In particular, tell your provider if you have or have a past history of: Cardiovascular risk that prevents you from partaking in sexual activity Chest pain requiring nitroglycerin Predisposition to priapism (painful erection that lasts >4 hours) Benign prostatic hyperplasia (BPH) and are being treated with alpha-blockers Ventricular outflow obstruction (e.g. aortic stenosis, idiopathic hypertrophic subaortic stenosis) Severely impaired autonomic control of blood pressure Myocardial infarction, stroke, or life-threatening arrhythmia Low or high blood pressure Cardiac failure or coronary artery disease causing unstable angina Anterior ischemic optic neuropathy (NAION) or a “crowded” optic disc. Bleeding disorders or ulcers Kidney or liver disease Pulmonary hypertension Retinitis pigmentosa Withholding or providing inaccurate information about your health and medical history in order to obtain treatment may result in harm, including, in some cases, death.

What are the most serious side effects that I or a caregiver should monitor for when taking tadalafil?

If you are experiencing a medical emergency, call 911 or seek immediate medical attention. You or a caregiver should carefully monitor for these side effects, especially in the beginning of treatment. Cardiac risk of sexual activity: ED medication should not be used by men for whom sexual activity is not advised because of their underlying cardiovascular status. Combination with other PDE-5 inhibitors: This compounded medication contains two prescription PDE-5 inhibitors, sildenafil and tadalafil. Monitor for signs of severely low blood pressure, such as dizziness or fainting, or prolonged erection. Do not take this medication more than once in a 24-hour period or within 24 hours of any other ED medications or products that contain tadalafil or sildenafil. Prolonged erections: Seek immediate emergency treatment for an erection lasting more than 4 hours. Effects on the eye: Seek medical care and stop medication if you experience a sudden loss of vision in one or both eyes. Sudden loss of vision could be a sign of non arteritic anterior ischemic optic neuropathy (NAION). Sudden hearing loss: Stop medication and seek prompt medical attention if you experience a sudden decrease or loss of hearing, which may be accompanied by ringing in the ears. Co-administering with alpha-blockers or other blood pressure-lowering drugs: If you are taking a medication to lower your blood pressure or taking an alpha-blocker, tadalafil may increase the blood-pressure lowering effect, leading to a sudden drop in blood pressure. When starting tadalafil, monitor carefully for signs of too low blood pressure, including dizziness, lightheadedness, or fainting. Kidney impairment: Talk to your Ro-affiliated provider about the appropriate dose of tadalafil if you have kidney impairment. Liver impairment: Talk to your Ro-affiliated provider about the appropriate dose of tadalafil if you have liver impairment. Alcohol: Drinking large amounts of alcohol (>5 units) with tadalafil can increase the potential of a sudden drop in blood pressure. Co-administering with CYP3A4 inhibitors: Talk to your Ro-affiliated provider about the appropriate dose of tadalafil if you are taking potent inhibitors of CYP3A such as ritonavir, ketoconazole, and itraconazole. Effects on bleeding: Tadalafil did not affect bleeding time when taken alone or with aspirin. Tell your Ro-affiliated provider if you have a bleeding disorder or ulcers. Sexually transmitted infections: Tadalafil does not protect against sexually transmitted diseases. Use safe sex practices.

What are the most common side effects of tadalafil?

Headache Indigestion Back pain Muscle pain Nasal congestion Flushing Pain in limbYou are encouraged to report negative side effects of prescription products to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.This information is not comprehensive. Please see the full Prescribing Information for complete safety information.